Laser-Induced Blood Coagulation for Surgical Application: A Scoping Review

Afnan Sedky Adly; Mahmoud Sedky Adly; Frederic Cuisinier; Jean-Christophe Egea; Ivan Panayotov; Aya Sedky Adly; Eve Malthiery

doi:10.1055/s-0043-1772573

Seminars in Thrombosis and Hemostasis, Table of Contents

Semin Thromb Hemost 2024; 50(02): 236-252
DOI: 10.1055/s-0043-1772573

Review Article

Laser-Induced Blood Coagulation for Surgical Application: A Scoping Review

Afnan Sedky Adly

¹LBN, Univ Montpellier, Montpellier, France

,

Mahmoud Sedky Adly

¹LBN, Univ Montpellier, Montpellier, France

²Royal College of Surgeons of Edinburgh, Scotland, United Kingdom

,

Frederic Cuisinier

¹LBN, Univ Montpellier, Montpellier, France

³CSERD, CHU Montpellier, Montpellier, France

⁴UFR Odontologie, Univ. Montpellier, Montpellier, France

,

Jean-Christophe Egea

¹LBN, Univ Montpellier, Montpellier, France

³CSERD, CHU Montpellier, Montpellier, France

⁴UFR Odontologie, Univ. Montpellier, Montpellier, France

,

Ivan Panayotov

¹LBN, Univ Montpellier, Montpellier, France

³CSERD, CHU Montpellier, Montpellier, France

⁴UFR Odontologie, Univ. Montpellier, Montpellier, France

,

Aya Sedky Adly

⁵IRMB, Univ Montpellier, INSERM, Montpellier, France

,

Eve Malthiery

¹LBN, Univ Montpellier, Montpellier, France

³CSERD, CHU Montpellier, Montpellier, France

⁴UFR Odontologie, Univ. Montpellier, Montpellier, France

› Author Affiliations

Abstract

There is a lack of evidence-based reviews on the effects of laser irradiation on blood coagulation in the literature, despite a large number of clinical trials. We therefore evaluated the available evidence on laser irradiation parameters used in coagulation of blood to optimize physical parameters. We performed a literature search for recent scientific studies indexed between 2017 and 2023 using the databases of PubMed and ScienceDirect. Articles were selected based on defined inclusion and exclusion criteria, and 78 publications in total were eventually included in this scoping review. The following were found to produce significant benefits in blood coagulation for surgical application: (1) dentistry and oral surgeries: 980 nm, 27 s, 2 W, 1502.7 W/cm2, 26.5 J, 622 J/cm2, 400 μm; (2) urogenital disorders: 532 nm, 4 s, 40 W, 10600 W/cm2, 1.3 J, 424 J/cm2, 600 μm; (3) ophthalmic disorders: 810 nm, 1 s, 1 W, 3540 W/cm2, 0.75 J, 1326 J/cm2, 100 μm; (4) embryological surgeries: 1064 nm, 10 s, 25 W, 35400 W/cm2, 262.5 J, 371000 J/cm2, 332.5 μm; (5) dermatological disorders: 1064 nm, 20 W, 2440 W/cm2, 0.1 J, 24 J/cm2, 670 μm; (6) gastrointestinal disorders: 532 nm, 3 s, 20 W, 1051 W/cm2, 120 J, 26500 J/cm2, 760 μm; (7) neurological surgeries: 2.5 s, 1.5 W, 1035 W/cm2, 2 J, 1584 J/cm2, 385 μm; (8) pulmonary disorders: 1320 nm, 5s, 35 W, 12450 W/cm2, 250 J, 65000 J/cm2, 700 μm (9) cardiovascular disorders: 1064 nm, 16.5 s, 5 W, 1980.5 W/cm2, 900 J, 760 J/cm2, 400 μm. In conclusion, our scoping review identifies that combining data from all clinically heterogeneous studies suggests that laser irradiation reflects an effective method for inducing blood coagulation in several medical fields.

Keywords

hemostasis - blood sealing - phototherapy - dose - laser coagulation - parameters

Full Text

References

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